Hypoglossal Nerve Disease refers to the impairment or dysfunction of the hypoglossal nerve, which controls the movement of the muscles in the tongue. It can result in various speech and swallowing difficulties, impacting the overall quality of life. Synonyms for this condition include Hypoglossal Nerve Dysfunction, Hypoglossal Nerve Disorder, Hypoglossal Nerve Impairment, and Hypoglossal Cranial Nerve Disease. These terms are interchangeably used to describe the same medical condition involving the hypoglossal nerve. Early diagnosis, proper medical intervention, and rehabilitative therapies can assist in managing the symptoms associated with Hypoglossal Nerve Disease and help patients regain functionality and improve their oral functions.