There are a plethora of synonyms for the phrase "losing wits." Among them are "going insane," "losing one's mind," "losing one's marbles," "cracking up," "flipping out," "losing it," "freaking out," "going crazy," "losing one's grip," and "falling apart." Each of these phrases suggests a gradual or sudden loss of control over one's thoughts, emotions, or behavior. They can often be used interchangeably, but some may be more appropriate in specific contexts. Regardless of the wording, experiencing a loss of sanity or control can be a stressful and challenging experience for anyone to go through.